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Eckert & Ziegler invests in capacity expansion for its GalliaPharm® production line

2017-05-12 / Eckert & Ziegler Radiopharma GmbH, a subsidiary of Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE 0005659700), signed a supply contract for components for a manufacturing line today, paving the way for the creation of additional capacities for its approved GalliaPharm® Germanium-68/Galliu (...) »

MDC to make research more publicly accessible in EU project

2017-05-10 / Supporting, organizing and carrying out research are the main tasks of scientific funding bodies and institutions. ORION, a Europe-wide collaborative project in the life sciences and biomedicine, aims to make these processes more transparent to the public. The Max Delbrück Center for Molecular Medic (...) »

Eckert & Ziegler: Sales Growth and Jump in Income in First Quarter

2017-05-09 / Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a Berlin-based company specializing in isotope technology for medical, scientific and industrial applications, increased its sales in the first quarter of 2017 by 5 % year on year to € 37.6 million. Earnings per share rose to € 0. (...) »

Fighting Cancer with Immunotherapy: Signaling Molecule Causes Regression of Blood Vessels

2017-04-27 / Immunotherapy with T-cells offers great hope to people suffering from cancer. Some initial successes have already been made in treating blood cancer, but treating solid tumors remains a major challenge. The signaling molecule interferon gamma, which is produced by T-cells, plays a key role in the th (...) »

How naked mole-rats defy lack of oxygen

2017-04-21 / When oxygen runs low in their underground burrows, naked mole rats have a unique method of survival. Their metabolism switches from a glucose-based system, which depends on oxygen, to one that makes use of fructose. For a while this suffices to protect sensitive organs such as the heart and brain. S (...) »

Mission Control for the body’s salt and water supplies: New studies show that salty food diminishes thirst while increasing hunger, due to a higher need for energy

2017-04-18 / We’ve all heard it: eating salty foods makes you thirstier. But what sounds like good nutritional advice turns out to be an old-wives’ tale. In a study carried out during a simulated mission to Mars, an international group of scientists has found exactly the opposite to be true. “Cosmonauts” who ate (...) »

Ferring announces exclusive agreement with Alrise Biosystems for the development of an injectable, controlled-release peptid

2017-04-10 / Ferring Pharmaceuticals and Alrise Biosystems announced today that the companies have entered into a development agreement with exclusive option rights for Ferring to leverage Alrise’s ImSus® Technology Platform for the development of an injectable, controlled-release formulation of a peptide therap (...) »

Research 4.0: Berlin Institute of Health moves to electronic lab notebooks

2017-04-06 / Starting in April 2017, the QUEST – Center for Transforming Biomedical Research at Berlin Institute of Health (BIH) will begin to implement electronic lab notebooks to manage research data. All BIH scientists at Charité – Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine in t (...) »

Eckert & Ziegler 2016 annual financial statements: Sales and profit according to plan. Gross profit margin up by 6%. Change in the Supervisory Board.

2017-03-23 / Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a Berlin-based company specializing in isotope technology for medical, scientific and industrial applications, reported sales of € 138.0 million (prior year: € 140.0 million) in fiscal year 2016. The slight decline in business vol (...) »

ERC funding for two MDC scientists

2017-03-22 / Medical imaging has an unavoidable side effect: MRI machines generate heat. Thoralf Niendorf has now been awarded an ERC Advanced grant to turn this feature into a tool to study the role of temperature in animal bodies. A second ERC Advanced Grant goes to Thomas Jentsch, who will explore the functio (...) »

Eckert & Ziegler to Recommend Dividend Payment

2017-03-21 / Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a specialist for isotope-based applications in medicine, science and industry achieved sales of 138 million EUR in the fiscal year 2016. As the Supervisory Board stated at its balance sheet meeting, the net profit was 9.5 million (...) »

A European success story

2017-03-14 / The European Research Council (ERC) is celebrating its 10th anniversary this week. Some 14 researchers at the Max Delbrück Center for Molecular Medicine have benefited so far from its funding – in some cases more than once. (...) »

A three-dimensional map of the genome

2017-03-09 / Cells face a daunting task. They have to neatly pack a several meter-long thread of genetic material into a nucleus that measures only five micrometers across. This origami creates spatial interactions between genes and their switches, which can affect human health and disease. Now, an international (...) »

Five New Chairs for Translational Medicine at Berlin Institute of Health: Joint appointments with Charité – Universitätsmedizin Berlin launched

2017-03-03 / Berlin Institute of Health (BIH) is offering the first chairs who will play a central role at BIH as the founding directors of new centers dedicated to key research areas. Five W3 professorship appointments were announced in the fields of digital health, clinical translational sciences, disease mode (...) »

OMEICOS Announces First Closing of €8.3 Million Series B Financing Round and the Initiation of Phase 1 Clinical Trial

2017-03-02 / Financing Provides Runway Beyond Completion of First-in-man Trial with Lead Compound OMT-28 for Treatment of Atrial Fibrillation (...) »

Inducing an identity crisis in liver cells may help diabetics

2017-02-13 / First successful reprogramming of liver cells to pancreas progenitor cells based on a single factor (...) »

Gamma oscillations coordinate food seeking

2017-02-06 / Seeking of food is a crucial survival instinct. However, until recently, little was known about how brain regulates this behavior. Scientists at the Leibniz-Institut für Molekulare Pharmakologie (FMP) and NeuroCure Cluster of Excellence in Berlin discovered a neuronal circuit which regulates the hyp (...) »

Antibody against bone marrow tumor developed at MDC is put into application

2017-01-24 / Researchers at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) have developed antibodies against the cell surface protein BCMA that promise to heal multiple myeloma, a type of bone tumor that is at present incurable. The biotechnology company Heidelberg Pharma will (...) »

MDC cancer researcher Roland Schwarz awarded BBAW prize

2016-11-14 / Dr. Roland F. Schwarz of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) conducts research on tumors using bioinformatics. He has just been awarded the Prize of the Berlin-Brandenburg Academy of Sciences and Humanities (BBAW), donated by the Monika Kutzner Foundatio (...) »

Eckert & Ziegler Q3/2016: Rise in Radiopharma segment income keeps the Group on track. Positive outlook for 2017

2016-11-03 / Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE 0005659700), a specialist for isotope-based applications in medicine, science and industry headquartered in Berlin, achieved sales of € 103.1 million in the nine months from January to September 2016. The sales figures were almost exactly on (...) »

Genome editing: efficient CRISPR experiments in mouse cells

2016-10-25 / In order to use the CRISPR-Cas9 system to cut genes, researchers must design an RNA sequence that matches the DNA of the target gene. Most genes have hundreds of such sequences, with varying activity and uniqueness in the genome. The search for the best sequences is therefore hardly achievable by ha (...) »

Disturbance wanted – Newly characterized protein interaction may help in search for new cancer-fighting drugs

2016-10-20 / Some anticancer agents intend to disturb the function of the p97 protein complex, which is essential for survival of cancer cells. A team of researchers of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) has now found a way to break up the p97 complex into its subun (...) »

Dechema colloquium „Games of tag – Letting protein modifications out of the lab“

2016-10-18 / For its very first edition, held at the innovative biomedical Campus Berlin-Buch, the DECHEMA colloquium will focus on protein modifications and their significant role in the development of new forms of therapy and diagnosis. We are proud to announce that Alfred Goldberg from the Harvard Medical Sc (...) »

Eckert & Ziegler awards prizes to young nuclear medicine researchers

2016-10-18 / This year’s Eckert & Ziegler Abstract Award went to five nuclear medicine specialists from Italy, Sweden and The Netherlands at the congress of the European Association of Nuclear Medicine (EANM) in Barcelona. The prizes were awarded for research work in the fields of oncological diagnostics. (...) »

MDC researchers discover new regulatory mechanism of important protein

2016-10-07 / Protein kinase A (PKA) is an important signaling enzyme that is found throughout the body and is involved in many cellular processes. It was thought to have been comprehensively studied, but scientists at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) have now disc (...) »

The life cycle of proteins

2016-10-07 / Some proteins behave in an unusual way: the older they become, the more stable they are. A research team at the Max Delbrück Center in the Helmholtz Association (MDC) has now published this surprising finding in the journal Cell. Their work has traced the life cycle of thousands of proteins from syn (...) »

Research on autophagy: Nobel Prize in Medicine for Yoshinor

2016-10-04 / Yoshinori Ohsumi will receive the nobel prize in medicine for the discovery of the autophagy mechanism. Volker Haucke has been interviewed as an expert: (...) »

Enjoy in moderation: compound from grapes protects cells from aging

2016-09-26 / Resveratrol, a compound found in red grapes, is famous for its potential health benefits. This positive impact is not due to the antioxidant effect of the substance or the specific activation of certain “aging genes,” as was previously thought. Instead, the substance has a pro-oxidative effect and p (...) »

Top of her class: Véronique Gebala of the MDC wins the Helmholtz award for best thesis

2016-09-23 / Each year the Helmholtz Association awards prizes for the best doctoral theses in its research areas – from Energy to Key Technologies. This year’s winner of the award in the field of Health is a recent graduate from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC): (...) »

Michael Gotthardt has been promoted to “Professor of Experimental and Translational Cardiology” at the MDC and Charité

2016-09-15 / With September 1, 2016 cardiologist and medical geneticist Prof. Michael Gotthardt of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) has been appointed W3 Professor for “Experimental and Translational Cardiology” at the Charité – Universitätsmedizin Berlin in coope (...) »

Two MDC researchers win European Research Council grants

2016-09-02 / An ERC double for the MDC: Dr. Jan Philipp Junker and Dr. Gaetano Gargiulo have each been awarded an ERC Starting Grant worth €1.5 million. Junker will be studying cellular processes in the heart of the zebrafish, while Gargiulo will conduct research into glioblastoma, the most common form of brain (...) »

Successful recycling: Protein quality control in the cell

2016-08-26 / A team led by MDC researcher Annika Weber has pinpointed the efficient mechanism used by cells to label faulty proteins. The findings, which provide important insights into the functioning of protein quality control in the cell, have now been published in the journal Molecular Cell. (...) »

Atomic structures of proteins elucidated: Biophysicist Adam Lange awarded the ICMRBS Founders' Medal

2016-08-24 / He has developed methods to visualise the complex architectures of proteins in atomic resolution using solid-state NMR. For this pioneering elucidation work, Prof. Adam Lange of the Leibniz-Institut für Molekulare Pharmakologie Berlin (FMP) has now been awarded the ICMRBS Founders' Medal in Kyoto. T (...) »

Stem cells of worms and humans more similar than expected

2016-08-10 / The same regulatory mechanisms are active in the stem cells of flatworms and humans. The transient form of genetic information, the RNA, is processed in a similar manner in the cells of both organisms. These mechanisms seem to be at work throughout the whole animal kingdom. Scientists from the Max D (...) »

Medical diagnosis of the future: Reinhart Koselleck Project for Leif Schröder

2016-08-02 / The physicist Leif Schröder has been granted funding totalling 1.525 million euros in the Koselleck programme of the DFG for highly innovative research into the detection of tumours (...) »

Eckert & Ziegler: Significant improvement in cost items in the first half year

2016-08-01 / In the first half of the year, Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE 0005659700), a specialist for isotope-based applications in medicine, science and industry headquartered in Berlin, posted a € 1.1 million rise in sales to € 70.1 million compared to the same period in the prior (...) »

A “time switch” in the brain improves sense of smell

2016-07-08 / When the brain processes olfactory stimuli, it differentiates between similar smells using subtly modulated signals. Brain examinations and behavioral studies in mice have now shown that neurons with inhibiting characteristics play a key role in this process. (...) »

Activation of glutamate receptors: seeing is believing

2016-06-29 / Our brain is a high-performance computer. One of the key players in this complex system is the AMPA-type glutamate receptor. It ensures that neurotransmission proceeds at a breakneck pace from cell to cell. Researchers from the Leibniz Institute for Molecular Pharmacology (FMP) in Berlin have now su (...) »

Insulin-sensitive fat leads to obesity

2016-06-21 / SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA was previously known for its protective role in Alzheimer’s disease. (...) »

ARCHES award for MDC researcher: High-resolution maps of genetic modifications

2016-06-15 / This year’s ARCHES prize, issued by the Minerva Stiftung, goes to systems biologist Dr. Jan Philipp Junker of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) and Prof. Erez Levanon of Bar-Ilan University in Israel. The award, conferred on June 14, 2016, will support (...) »

Wiretapping the senses

2016-06-03 / The Poulet lab monitors a conversation between sensory perception and behavior in the mouse brain. Many types of sensory information enter the brain at a structure called the primary sensory cortex, where they are processed by different layers of cells in ways that ultimately influence an animal’s p (...) »

Preeclampsia: Inflammation of the placenta interferes with fetal development

2016-06-02 / Preeclampsia is one of the most common complications to occur during pregnancy, yet its causes are still unknown. A new study involving patients, cell cultures and animal experiments has now shown that those affected by the disease have lower quantities of the placenta’s immune protein CD74, and tha (...) »

Berlin-Buch at the BIO INTERNATIONAL CONVENTION

2016-06-01 / The BBB Management GmbH will represent the Health Location Berlin-Buch in the German Pavilion at the most important global event for the biotechnology industry, the BIO International Convention. The BIO will take place June 6-9, 2016 in San Francisco, USA. Together with Berlin Partner and ZukunftsAg (...) »

Humboldt award winner Nir Friedman to be guest researcher at the MDC

2016-05-23 / Israeli systems biologist and bioinformatician Prof. Nir Friedman of the Hebrew University of Jerusalem (HUJI) is one of this year’s recipients of the prestigious Humboldt Research Award. Friedman’s host institution in Germany will be the Max Delbrück Center for Molecular Medicine in the Helmholtz A (...) »

Cancer-fighting gene therapy: from research to application

2016-05-10 / Whether repairing faulty genes or introducing characteristics by delivering new genes into cells, gene therapy holds great potential for personalized medicine. However, safe, efficient and cost-effective therapies of this kind are currently few and far between for clinical use. Researchers at the Ma (...) »

Eckert & Ziegler: Sales Growth and Strong Operating Result in the First Quarter

2016-05-10 / Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a Berlin-based company specializing in isotope technology for medical, scientific and industrial applications, reported sales of € 35.8 million (+6%) in the first quarter of 2016. All segments registered organic growth. However, t (...) »

Oscillations determine whether blood vessels grow thicker or branch

2016-04-26 / As blood vessels grow, the cells that compose them must make a choice between forming side-branches or expanding the vessel surface and increasing its diameter. Now Prof. Holger Gerhardt at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) and his international resear (...) »

Eckert & Ziegler subscribes to capital increase at BEBIG

2016-04-25 / At today’s meeting, the Board of Directors of Eckert & Ziegler BEBIG s.a. in Belgium resolved to propose to the Annual General Meeting on June 9, 2016 a capital increase with the exclusion of subscription rights of minority shareholders. Eckert & Ziegler AG, which already owns just under 75% of the (...) »

Eckert & Ziegler 2015 Annual Financial Statements: Sales Growth of 10%. Profit Increase of 58% thanks to Extraordinary Income.

2016-03-23 / Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a Berlin-based company specializing in isotope technology for medical, scientific and industrial applications, reported sales of € 140.0 million in fiscal year 2015. This corresponds to an increase of € 12.8 million, or 10%, on th (...) »

MDC founding director Detlev Ganten celebrates his 75th birthday

2016-03-22 / Medic, science manager, innovator: Prof. Detlev Ganten, founding director of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), turns 75 on March 28, 2016. (...) »

MDC researcher Markus Landthaler receives science prize

2016-03-21 / The cell regulates the activity of its genes in various ways. The GlaxoSmithKline Foundation awards Dr. Markus Landthaler of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) for his innovative research about gene regulation. The systems biologist Landthaler wants to (...) »

More than 200 high school students explore the world of stem cells

2016-03-16 / On March 11, 2016 stem cells were on the timetable for a number of students in Berlin with a keen interest in biology. More than 200 high school students from 15 Berlin schools attended Germany’s first UniStem Day, hosted by the Max Delbrück Center for Molecular Medicine (MDC) in Berlin-Buch. The ne (...) »

Blood vessels sprout under pressure

2016-03-01 / It is blood pressure that drives the opening of small capillaries during angiogenesis. A team of researchers led by Prof. Holger Gerhardt of the MDC observed the process for the first time and published their findings in Nature Cell Biology. The scientists showed how the pressure exerted by the bloo (...) »

Gene therapy: T cells target mutations to fight tumors

2016-02-19 / An international research team from the Max Delbrück Center for Molecular Medicine (MDC) and the Charité (partners in the Berlin Institute of Health, BIH), the Humboldt University Berlin and the University of Chicago has successfully modified immune cells to recognize and specifically target tumor c (...) »

Eckert & Ziegler expands cooperation program with drug developers in the field of nuclear medicine

2016-02-03 / Eckert & Ziegler AG, a specialist for isotope-based applications in medicine, science and industry, is expanding its cooperation program with promising drug developers in the field of nuclear medicine and will support Curasight, a spin-off based on research by the group of Professor Andreas Kjaer at (...) »

Ischemic renal failure and organ damage: a new mouse model holds the key

2016-01-29 / Every year acute renal failure affects over 13 million people and leads to 1.7 million deaths across the globe.It often develops when an insufficient supply of oxygen reaches the kidneys, a condition called ischemia. Working with their colleagues from the MDC, the Charité and FMP in Berlin and Hanno (...) »

Hacking the programs of cancer stem cells

2016-01-25 / All of the cells in a tumor are the offspring of a single, aberrant cell, but they are not all alike. Only a few retain the capacity of the original cell to create an entire tumor. Such cancer stem cells can migrate to other tissues and become fatal metastases. To fully cure a patient’s cancer, it i (...) »

How to detect and preserve human stem cells in the lab

2016-01-22 / Human stem cells that are capable of becoming any other kind of cell in the body have previously only been acquired and cultivated with difficulty. Scientists at the Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association have now presented details of a method to detect such pl (...) »

Muscle weakness: Berlin scientists unravel defects in rare hereditary disease myotubular myopathy

2016-01-13 / Tiny deviations in the body's cells can sometimes have severe consequences. Researchers from Berlin have discovered why cells from patients suffering from the rare muscular disease myotubular myopathy cannot function properly. Through the paper published in Nature, it has become clear how a dynamic (...) »

EPO Berlin‐Buch GmbH starts strategic collaboration with NexusPharma to foster its market position in the USA

2016-01-08 / Experimental Pharmacology & Oncology Berlin‐Buch GmbH (EPO) has entered into a partnership with NexusPharma, a Philadelphia‐based preclinical pharmacological testing company, to facilitate introduction of their Berlin‐based collection of primary patient‐derived tumor models and EPO’s new humanized t (...) »

Glycotope names Paul G Higham as new Chief Executive Officer

2016-01-07 / Glycotope GmbH, a global leader in glyco-optimization of biopharmaceuticals, today announced the appointment of Paul G Higham as its new Chief Executive Officer (CEO), effective immediately. (...) »

Superactivation at synapses?

2016-01-05 / Nerve cells have to react extremely quickly, but depending on the task they are supposed to perform they often need to work more slowly. Berlin scientists have now shown that a receptor in the synapse can adapt to follow both regimes. It’s another example of the amazing flexibility of the brain, man (...) »

Changing Architecture: A new understanding of the spatial organization of our genome

2015-12-23 / It has now been 15 years since scientists celebrated the completion of the human genome. At that point, scientists had determined the entire sequence of the genetic letters making up our DNA. It is now known that this was only an initial step in a long journey: in addition to the chemical letters, i (...) »

Technology transfer success: US approval for bleeding disorder drug

2015-12-21 / “VONVENDI [von Willebrand factor (Recombinant)]”, the new drug from Baxalta Incorporated, a global biopharmaceutical company recently spun off from Baxter International, has just been approved by the United States Food and Drug Administration. It is the first, and so far the only, recombinant protei (...) »

Drug against aggressive leukemia gets approval for Europe

2015-12-14 / The drug Blincyto (Blinatumomab) has now been approved by the European Medicines Agency. Blinatumomab is used to treat patients with a very aggressive form of blood cancer, and is the result of work carried out at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) over (...) »

Sudden cardiac death: large study to improve risk assessment

2015-12-07 / One of the most common causes of sudden cardiac death in young people is a genetic condition known as hypertrophic cardiomyopathy (HCM). However, it is difficult to assess the risk of sudden cardiac death among people with this condition using current methods. The National Institutes of Health (NIH) (...) »

Eckert & Ziegler to sell US seed business

2015-11-30 / Eckert & Ziegler BEBIG s.a. (EZB), Eckert & Ziegler AG’s medical device division, is to sell its US seed business to the US-based Theragenics Corporation. This was decided by the Supervisory Board during today’s meeting. The transaction is expected to be completed by the end of 2015. The parties hav (...) »

Neurodermatitis genes influence other allergies

2015-11-06 / There’s a typical "career" for some allergic people, and it starts very early on the skin: babies develop atopic dermatitis, food allergies may follow, then comes asthma and later on hay fever. A group of scientists led by Ingo Marenholz and Young-Ae Lee at the Max Delbrück Center for Molecular Medi (...) »

Eckert & Ziegler: Successful performance in first nine months of 2015. Moderate third quarter.

2015-11-05 / Berlin-based Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a specialist for isotope technology applications in medicine, science and industry, achieved sales of € 102.7 million in the nine months from January to September 2015. Compared to the same period in the prior year, (...) »

OMEICOS Receives BMBF Research Grant to Advance its Novel Approach to Treat Atrial Fibrillation

2015-11-02 / OMEICOS Therapeutics, a biopharmaceutical company developing first-in-class small molecule therapeutics for the prevention and treatment of cardiovascular diseases including atrial fibrillation, today announced the approval of an approximately €1.7 million grant by the German Ministry of Education a (...) »

Ten new Genetic Risk Loci for Eczema Discovered – International Study with over 50,000 Eczema Patients

2015-10-20 / Researchers in Europe, Australia, Asia, and America have now discovered ten new risk loci for the chronic inflammatory skin disease eczema. Among the new candidate genes for eczema, the researchers came upon genes that are important for the innate immune system and for the development and function o (...) »

From Vancouver to Berlin: W3 Professorship for Bioinformatician Irmtraud Meyer at the FU Berlin and the Max Delbrück Center

2015-10-19 / The bioinformatician Irmtraud Meyer of the University of British Columbia in Vancouver, Canada, has accepted the appointment to a W3 professorship for “Bioinformatics of the RNA Structure and Transcriptome Regulation” at the Freie Universität Berlin (FU) in cooperation with the Berlin Institute for (...) »

Pumpkin-shaped molecule enables 100-fold improved MRI contrast: new agent for detecting pathological cells

2015-10-13 / Assuming that we could visualise pathological processes such as cancer at a very early stage and additionally distinguish the various different cell types, this would represent a giant step for personalised medicine. Xenon magnetic resonance imaging has the potential to fulfil this promise – if suit (...) »

Eckert & Ziegler awards prizes to young nuclear medicine researchers

2015-10-13 / This year’s Eckert & Ziegler Abstract Award went to five nuclear medicine specialists from Germany, the Netherlands, the United Kingdom and USA at the congress of the European Association of Nuclear Medicine (EANM) in Hamburg. The prizes were awarded for research work in the fields of oncological an (...) »

New field of application for versatile helper

2015-10-12 / Small heat shock protein as model for Alzheimer medication - In Alzheimer’s disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerati (...) »

Green waves in the brain: theta oscillations coordinate navigation and movement

2015-10-09 / Using light pulses, Berlin scientists have recently managed to control theta oscillations in mouse brain. They discovered that these brain waves coordinate movement - enabling signaling between distant brain regions – a common code for controlling mental states and behavior. Author: modifiziert Bend (...) »

Helmholtz International Fellow Award for Professor Amanda Fisher from London – Prize Award Ceremony at the Max Delbrück Center

2015-10-06 / The British cell biologist Professor Amanda Gay Fisher of Imperial College (ICL) London has been honored with the Helmholtz International Fellow Award for her excellent research. In a prize ceremony at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) in Berlin, Germa (...) »

Merck Millipore Adds Protein Pegylation to Portfolio of Services for Biopharmaceutical Industry through Collaboration with celares GmbH

2015-10-05 / Merck Millipore, the Life Science business of Merck, announced a collaboration with celares GmbH to provide pegylation services to customers developing protein-based therapeutics and biosimilars. The new service offering enabled by the collaboration includes feasibility studies, process and analytic (...) »

Big eyes! – MDC Researchers Identify Cause of Inherited Form of Extreme Nearsightedness

2015-10-02 / “Why, Grandma, what big eyes you have!” Though similar in appearance, the hidden cause of those big eyes Little Red Riding Hood notices in Grimms’ fairy tale has nothing to do with the hidden cause of enlarged eyeballs in buphthalmia, a genetic mechanism causing this devastating eye disease which ha (...) »

Full Professorship for Dr. Wei Chen from the MDC

2015-09-30 / Geneticist and genome researcher Dr. Wei Chen of the Berlin Institute for Medical Systems Biology (BIMSB) at the Max Delbrück Center for Molecular Medicine in the Helmholtz-Association (MDC) has become full professor for “Functional Genomics and Systems Biology” at Charité – Universitätsmedizin Berl (...) »

Dr. Harald Hasselmann appointed as new managing director of Eckert & Ziegler BEBIG

2015-09-03 / As part of the restructuring measures at medical technology company Eckert & Ziegler BEBIG (Euronext: EZBG; Reuters: EZBG.BR; Bloomberg: EZBG:BB), the Board of Directors has appointed business administration expert Dr. Harald Hasselmann (aged 48) as the new commercial managing director for sales and (...) »

MDC and Charité Researchers: MACC1 Gene Is an Independent Prognostic Biomarker for Survival in Klatskin Tumor Patients – Aid in Deciding Whether Surgery Is Best Option

2015-08-31 / Bile duct cancer is rare and is usually detected too late. Often only extensive liver surgery can help or, in rare cases, liver transplantation. But which patients will benefit from surgery and which will not, because their risk of cancer recurrence is too high? With the oncogene MACC1 as a biomarke (...) »

MDC and MHH Researchers Show How Dynamin Mediates Membrane Constriction and Scission – A Vital Process

2015-08-25 / Cells continually form membrane vesicles that are released into the cell. If this vital process is disturbed, nerve cells, for example, cannot communicate with each other. The protein molecule dynamin is essential for the regulated formation and release of many vesicles. Scientists of the Max Delbrü (...) »

Skeletal Muscle Atrophy in Congestive Heart Failure – Mechanism Elucidated by MDC and Charité Researchers

2015-08-10 / It is a paradox: Patients with advanced congestive heart failure lose skeletal muscle mass, but their heart muscles become enlarged to provide the body with an adequate supply of blood and thus with oxygen. It has long been known that the protein angiotensin II plays a villainous role in this proces (...) »

Record quarter despite restructuring expenses

2015-08-04 / Berlin-based Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a specialist for isotope technology applications in medicine, science and industry, recorded one of its most-successful quarters ever in spite of considerable provisions being set aside for risk provisioning and the r (...) »

RNA-binding Protein Influences Key Mediator of Cellular Inflammation and Stress Responses

2015-07-31 / Messenger (mRNA) molecules are a key component of protein biosynthesis. They are first transcribed as a “working copy” of the DNA and then translated into protein molecules. RNA-binding proteins such as RC3H1 (also known as ROQUIN) regulate the degradation of the mRNA molecules and thus prevent the (...) »

Getting to the bottom of ageing

2015-07-30 / The question of why we age is one of the most fascinating questions for humankind, but nothing close to a satisfactory answer has been found to date. Scientists at the Leibniz-Institut für Molekulare Pharmakologie in Berlin have now taken one step closer to providing an answer. They have conducted a (...) »

Georg Forster Research Award of the Alexander von Humboldt Foundation Granted to Brazilian Cardiovascular Researcher – Cooperation with the MDC

2015-07-27 / The cardiovascular researcher Professor Robson Augusto Souza dos Santos of the Federal University of Minas Gerais in Belo Horizonte, Brazil, has been awarded the Georg Forster Research Award of the Alexander von Humboldt Foundation (AvH). The award will enable him to intensify his longstanding coope (...) »

WISE s.r.l. raises EUR 3 Million for clinical development of novel neuromodulation implants for spinal cord stimulation

2015-07-17 / WISE Srl, a medical device company developing next-generation implantable neuromodulation leads has closed in June of a EUR 3 million series A financing round, led by Principia SGR, an Italian Venture Capital firm. Existing investors High-Tech Gründerfonds, Atlante Seed and b-to-v Partners joined th (...) »

MDC Symposium in Honor of Professor Carmen Birchmeier-Kohler on the Occasion of her 60th Birthday

2015-07-10 / The Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) has honored Professor Carmen Birchmeier-Kohler with a symposium about the latest findings in the neurosciences entitled “Frontiers in Developmental Neuroscience”. The internationally renowned developmental biologist an (...) »

IPSEN has closed acquisition of Octreopharm Sciences GmbH

2015-06-30 / OctreoPharm Sciences GmbH (OPS), based in Berlin (Germany), announced that the radiopharmaceutical company has closed a purchase agreement with French pharmaceutical company IPSEN for all shares of OPS. The deal has an overall value of about 50 mm EUR, including clinical development and commercial m (...) »

Slight Differences – New Insights into the Regulation of Disease-Associated Genes

2015-06-10 / Researchers of the Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, in collaboration with the National Heart Research Institute in Singapore (NHRIS), have gained new insights into the regulation of disease-associated genes. They used a new technique that enables them to (...) »

IPSEN to acquire all shares in Octreopharm Sciences GmbH

2015-05-19 / Eckert & Ziegler Radiopharma GmbH (EZR) and a group of start-up investors have signed a purchase agreement with French pharmaceutical company IPSEN for all shares of Octreopharm Science GmbH (OPS), a drug development company located in Berlin-Buch. The deal, which is subject to various conditions pr (...) »

MDC and Charité Researchers Identify Gene Responsible for Hypertension and Brachydactyly

2015-05-11 / Individuals with this altered gene have hereditary hypertension (high blood pressure) and at the same time a skeletal malformation called brachydactyly type E, which is characterized by unusually short fingers and toes. The effect on blood pressure is so serious that – if left untreated – it most of (...) »

Eckert & Ziegler: positive start to the year 2015

2015-05-05 / Berlin-based Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a specialist for isotope technology applications in medicine, science and industry, saw double-digit percentage increases in sales and earnings in the first quarter of 2015. (...) »

Systematic Interaction Network Filtering in Biobanks: MDC Neurobiologists Identify Protective Protein against Huntington’s Disease

2015-04-24 / While seeking targets to attack Huntington’s disease, an incurable inherited neurodegenerative disorder, neurobiologists of the research group led by Professor Erich Wanker of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association found what they were looking for. Using a filter (...) »

Eckert & Ziegler’s SagiNova® afterloader receives FDA market clearance

2015-04-23 / Eckert & Ziegler has received market clearance from the U.S. Food and Drug Administration (FDA) for its new SagiNova® afterloader. The receipt of approval marks yet another milestone in the company’s expansion in the U.S. brachytherapy market. North America is the largest homogeneous market for brac (...) »

LEIBNIZ-DRUG OF THE YEAR: HOPE FOR PATIENTS HAVING A SKIN DISEASE

2015-04-22 / Award for a novel therapeutic approach for ichthyosis, a rare skin disease for which no therapy is available so far. The Leibniz Research Alliance "Bioactive Compounds and Biotechnology" recognizes the achievements of Margitta Dathe’s group at the Leibniz-Institut für Molekulare Pharmakologie (FMP) (...) »

OMEICOS Therapeutics Raises EUR 6.2 Million in Series A to Advance Lead Candidate in Atrial Fibrillation

2015-04-15 / OMEICOS Therapeutics, a biopharmaceutical company developing first-in-class small molecule therapeutics for the prevention and treatment of cardiovascular diseases including atrial fibrillation (AF), today announced that it has raised EUR 6.2 million in a Series A round. Participating in the round w (...) »

Silence Therapeutics Scrounges Up $58 Million to Expand RNA Research

2015-04-09 / Silence Therapeutics raised $58.2 million to develop its genetic RNA therapeutics technologies, Reuters reported Thursday morning. (...) »

Eckert & Ziegler’s Annual Report 2014: Weak Therapy segment puts a strain on consolidated profit

2015-03-26 / Berlin-based Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a specialist for isotope technology applications in medicine, science and industry, generated earnings of € 2.3 million in the 2014 fiscal year, which is 25 % less than in the prior year. The decline in consolidated p (...) »

MDC Researchers Greatly Increase Precision of New Genome Editing Tool – “One of the hottest topics in science and an innovative field”

2015-03-25 / CRISPR-Cas9 is a powerful new tool for editing the genome. For researchers around the world, the CRISPR-Cas9 technique is an exciting innovation because it is faster and cheaper than previous methods. Now, using a molecular trick, Dr. Van Trung Chu and Professor Klaus Rajewsky of the Max Delbrück Ce (...) »

Eckert & Ziegler to Recommend Dividend Payment

2015-03-17 / The company Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700) increased its sales by 9 % to € 127 million in fiscal year 2014. As the Supervisory Board stated at its balance sheet meeting held today, net profit for the year was € 1.28 per share, or € 6.8 million in total (prior ye (...) »

MDC Researchers Discover New Signaling Pathway in Embryonic Development

2015-03-11 / During pregnancy, the mother supplies the fetus with nutrients and oxygen via the placenta. If placental development is impaired, this may lead to growth disorders of the embryo or to life-threatening diseases of the mother such as preeclampsia, a serious condition involving high blood pressure and (...) »

New Insights on DNA Transcription: Start Region Shown to Be Directional

2015-02-19 / To bind enzymes that read a gene at the right place, the DNA contains so-called promoters, recognition sequences that are located near the transcription start sites of the genes. Since the advent of high-throughput sequencing technology, which enables the precise investigation of gene expression pat (...) »

Reprogramming Liver Cells into Pancreas Cells - New European Research Grant for Diabetes Researcher Dr. Francesca Spagnoli of the MDC

2015-01-07 / Diabetes researcher Dr. Francesca Spagnoli of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch has been awarded an extra research grant from the European Research Council (ERC). This Proof-of-Concept (PoC) grant is endowed with 150,000 euros over a period of two years. It is designed (...) »

Curt Meyer Memorial Prize for Dr. Jane Holland of the MDC: Main Driver Identified for Aggressive Form of Breast Cancer

2014-12-11 / The Australian cancer researcher Dr. Jane Holland of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch was honored on the evening of December 10, 2014 with the Curt Meyer Memorial Prize. She received the prize, which is endowed with 10,000 euros, for her study on basal breast cancer, (...) »

ERC Starting Grants for Two Researchers of the MDC

2014-12-09 / Two researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch will receive more than 3 million euros in research funding from the European Research Council (ERC) in Strasbourg. Cancer researcher Dr. Michela Di Virgilio and systems biologist Dr. Baris Tursun of the Berlin Instit (...) »

Eckert & Ziegler receives approval for gallium-68 generator for cost-effective diagnosis of cancer

2014-12-04 / Eckert & Ziegler Radiopharma GmbH has received approval from the Federal Institute for Drugs and Medical Devices (BfArM) for its pharmaceutical 68Ge/68Ga generator for the German market. The 68Ge/68Ga generator is the world’s first, approved radionuclide generator to use a radionuclide for positron (...) »

Eckert & Ziegler Q3/2014: Sales up, income mixed

2014-11-06 / Berlin-based Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a specialist in isotope technology applications for medicine, science and industry, has increased sales by 7% year on year to € 92.6 million in the first nine months of 2014. Adjusted for exchange rates, sales growth (...) »

Berlin Cures: Novel treatment targeting the cause of heart failure

2014-11-05 / Ascenion receives equity in Charité and MDC spin-off Berlin Cures is the first joint spin-off to be launched by the Charité – Universitätsmedizin Berlin (Charité) and the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch. The company is developing a new aptamer-based causal treatment for (...) »

Eckert & Ziegler awards prizes to young nuclear medicine researchers

2014-10-21 / This year’s Eckert & Ziegler Abstract Award went to five nuclear medicine specialists from Australia, the United Kingdom, Germany, Italy and Canada at the congress of the European Association of Nuclear Medicine (EANM) in Gothenburg. The prizes were awarded for research work in the fields of cancer (...) »

Development candidate SOMscan® against neuroendocrine tumors receives orphan drug status from the FDA

2014-10-16 / OctreoPharm Sciences GmbH, in which Eckert & Ziegler Radiopharma GmbH holds an interest, has received the coveted and financially rewarding orphan drug status from the US Food and Drug Administration (FDA) for its new diagnostic agent SOMscan®. This status allows for a more cost effective approval p (...) »

Researchers in Berlin and Bath Identify “Naïve-Like” Human Stem Cells

2014-10-16 / In their search for the earliest possible stage of development of human embryonic stem cells (hESCs) that still have the potential to develop into any types of body cells and tissue, researchers from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, and the University of Bat (...) »

Professor Walter Rosenthal Assumes Presidency of Jena University – Professor Thomas Sommer Becomes Interim Director of the MDC

2014-10-16 / On October 16, 2014, Professor Walter Rosenthal, former Chair of the Board of Directors and Scientific Director of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch since 2009, assumed his new position as President of the Friedrich Schiller University Jena. He was elected on May 23, 2 (...) »

The MDC and the campus mourn Andrej Nikolaevič Timoféeff

2014-09-18 / Prof. Andrej Nikolaevič Timoféeff passed away at the age of 87 on September 9, 2014. He was the son of Elena and Nikolaj V. Timoféeff-Ressovsky, two famous geneticists that worked on the Berlin-Buch campus in the 1930s and 1940s. Nikolaj Timoféeff-Ressovsky published a study with Max Delbrück and Ka (...) »

Frost & Sullivan Honours ALRISE for Resolving Key Unmet Needs in Drug Delivery

2014-09-06 / Based on Frost & Sullivan’s recent analysis of the European drug delivery landscape, ALRISE Biosystems GmbH was recognised as winner of the 2014 Frost & Sullivan Technology Innovation Leadership Award. (...) »

Eckert & Ziegler takes over Brazilian isotope specialists – stronger presence in South America

2014-09-03 / Eckert & Ziegler Strahlen- und Medizintechnik AG acquired the Isotope business unit of REM Indústria e Comércio Ltda. (REM), based in Sao Paulo, Brazil, effective September 1, 2014 via its subsidiary Eckert & Ziegler Isotope Products Holdings GmbH. The approximately 30 employees have been integrated (...) »

From the U.S. to Berlin: Junior Research Group Leaders for the MDC and NeuroCure

2014-09-01 / Cancer research and the neurosciences at the Max Delbrück Center for Molecular Medicine (MDC) have been strengthened. The biologist Dr. Michela Di Virgilio from The Rockefeller University in New York, USA began work in September as Helmholtz junior research group leader at the MDC, a research instit (...) »

Angiogenesis Specialist Begins Work at MDC, Charite, DZHK and BIH in Berlin

2014-09-01 / Several research institutions in Berlin have jointly succeeded in attracting the angiogenesis specialist Dr. Holger Gerhardt to the capital city. Since the beginning of September he is research group leader at the Max Delbrück Center for Molecular Medicine (MDC) and at the Berlin Institute of Health (...) »

New Research Method Opens Door to Therapy with Human Muscle Stem Cells: Scientists and Physicians in Germany Collaborate to Develop Promising Method

2014-08-27 / Muscle stem cells are essential for the repair of muscle damage, but all attempts to manipulate human muscle stem cells for therapy have thus far failed. Now Dr. Andreas Marg and Professor Simone Spuler of the Experimental and Clinical Research Center (ECRC), a joint cooperation between the Max Delb (...) »

Eckert & Ziegler: Sales growth in first half of year, no growth in earnings so far

2014-08-05 / Berlin-based Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700), a specialist in isotope technology applications for medicine, science and industry, has increased sales by 8 % year on year to € 31.2 million in the second quarter of 2014. Sales rose by € 6.6 million, or 12 %, to € 6 (...) »

Eckert & Ziegler: Cancer irradiation systems installed in Ethiopia for the first time

2014-08-04 / For the first time, a system designed to provide radiation in treating gynecological tumors with brachytherapy sources has been installed in a hospital in Addis Ababa, the capital of Ethiopia, as part of a United Nations aid program for expanding healthcare in Africa. Brachytherapy involves miniatur (...) »

Eckert & Ziegler: First patient enrolment for SOMscan®

2014-07-01 / OctreoPharm Sciences GmbH, a development company for radiopharmaceuticals, treated its first patients in a Swiss university hospital as part of the clinical trials for its new diagnostic agent SOMscan®. According to statements by the doctors, the trials proceeded without complication. SOMscan® is us (...) »

Eckert & Ziegler: European approval process for Gallium-68 generator successfully completed – world’s first authorization for new, inexpensive method for PET radiolabeling

2014-06-27 / Eckert & Ziegler Radiopharma GmbH has received a recommendation from the European Medicines Agency for approval of its pharmaceutical 68Ge/68Ga generators. This achievement marks the conclusion of a comprehensive decentralized evaluation procedure and the first time a gallium generator has been appr (...) »

Rome’s Sapienza University Awards Honorary PhD to MDC Researcher Nikolaus Rajewsky

2014-06-12 / Professor Nikolaus Rajewsky of the Max Delbrück Center for Molecular Medicine (MDC) was awarded an honorary PhD in human biology and medical genetics by Sapienza University of Rome on June 11, 2014. The award was given in recognition of his achievements in systems biology, in particular for his cont (...) »

Humboldt Research Award Granted to Cancer Researcher Hua Eleanor Yu

2014-06-05 / Cancer researcher and immunologist Professor Hua Eleanor Yu of the Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA, has been awarded the Humboldt Research Award of the Alexander von Humboldt Foundation (AvH) at an award ceremony in Berlin in the evening of June 4th, (...) »

Turbocharger for nerve cells: operation of ADHS gene investigated

2014-06-05 / Individuals with attention-deficit / hyperactivity syndrome (ADHS) often have a higher frequency of mutations in the gene for GIT1 – the research group headed by Volker Haucke has now established the role played by this protein at neuronal synapses. In a second study, the group elucidated fundamenta (...) »

How the Environment and Genetics Impact Our DNA

2014-06-02 / The impact of the environment on our genetic makeup has long been a topic of discussion among researchers. Now a European consortium (EURATRANS) headed by Professor Norbert Hübner of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch has taken the opposite approach. The scientists have (...) »

MDC Researchers Gain New Insights into Epilepsy

2014-03-21 / Just as each musician in an orchestra contributes to the overall sound of a musical piece, different types of nerve cells in the brain make up the symphony of our consciousness. They regulate and coordinate the activity of groups of neurons that represent parts of information, which they then may tr (...) »

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